Upstream process - in bioreactors (up to 200L), downstream process - purification of viruses and proteins, conjugation or chemical modification of proteins on a pilot scale.
• Production of non-clinical and clinical batches under GMP conditions for phase I, II and III studies, from production and purification platforms.
• Formulation, Aseptic filling, Lyophilization; Filling and Crimping.
Bio-Manguinhos/Fiocruz 2019
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